Lab News

A new study from the Ploss Lab published in Nature Communications

Congratulations to Florian Douam for the publication of his recent work in Nature Communications:

Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome

Publication: http://www.nature.com/articles/ncomms14781

And also featured in: https://blogs.princeton.edu/research/2017/03/14/2003/

Welcome to our new undergrads Evelyn and Nicolas

Welcome to Evelyn Wu (’19) and Nicolas Archer (’19) who joined the Ploss lab this month

Bridging the gap: a humanized mouse model for hepatitis B

Our recent story published in the journal "virology" on humanized mouse model for hepatitis B is highlighted in "Virologyhighlights" this week: Click here to access the post.

New publications from the Ploss Lab

Congratulations to Markus von Schaewen, Benjamin Winer and Qiang Ding for their recent publications in Virology, Journal of Virology, MBio and PNAS :

Ding Q, Heller B, Capuccino JM, Song B, Nimgaonkar I, Hrebikova G, Contreras JE, Ploss A. 2017. Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles. Proceedings of the National Academy of Sciences of the United States of America.

Winer BY, Huang T, Low BE, Avery C, Pais MA, Hrebikova G, Siu E, Chiriboga L, Wiles MV, Ploss A. 2016. Recapitulation of treatment response patterns in a novel humanized mouse model for chronic hepatitis B virus infection. Virology 502:63-72.

Ding Q, von Schaewen M, Hrebikova G, Heller B, Sandmann L, Plaas M, Ploss A. 2016. Mice expressing minimally humanized CD81 and occludin genes support hepatitis C virus uptake in vivo. Journal of virology.

von Schaewen M, Dorner M, Hueging K, Foquet L, Gerges S, Hrebikova G, Heller B, Bitzegeio J, Doerrbecker J, Horwitz JA, Gerold G, Suerbaum S, Rice CM, Meuleman P, Pietschmann T, Ploss A. 2016. Expanding the Host Range of Hepatitis C Virus through Viral Adaptation. mBio 7.

Welcome to Lei Wei

Welcome to Lei Wei, a new post-doc in the Ploss Lab, who recently obtained a Ph.D. from the Memorial Sloan Kettering Cancer Center.