The Notterman lab studies genetic and epigenetic mechanisms that contribute to behavioral and health outcomes in children. Members of the lab are part of an interdisciplinary team that includes faculty and students in molecular biology, sociology, computer science, and psychology. This work is centered about the Fragile Family and Child Well Being Study, a longitudinal study of disadvantaged mothers and children now in its 17th year. Our group produces and analyzes the genetic (genotype), epigenetic (DNA methylation) and telomere length data that forms the basis of research on the biological links between a child’s environment and her health and behavioral life course. Lab members are also exploring the role of host cell telomerase in mediating cytomegalovirus infection, repetitive head injury using a Drosophila model, and biochemical effects of chronic stress.