Korennykh Lab Publications

Recent Publications

2014 Yuchen Han, Jesse Donovan, Sneha Rath, Gena Whitney, Alisha Chitrakar and Alexei Korennykh
Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response
Science (2014)

2013 Jesse Donovan, Matthew Dufner, Alexei Korennykh
Structural basis for cytosolic double-stranded RNA surveillance by human OAS1
PNAS (2013)

2012 Yuchen Han, Gena Whitney, Jesse Donovan, Alexei Korennykh
Innate Immune Messenger 2-5A Tethers Human RNase L into Active High-Order Complexes
Cell Reports (Cell Press) 2(4), (2012) pp. 902-913

2012 Alexei V Korennykh, Peter Walter
Structural basis of the unfolded protein response
Annu. Rev. Cell Dev. Biol. (2012) Vol. 28 pp. 21.1–21.27

2011 Alexei V Korennykh, Andrei A Korostelev, Pascal F Egea, Janet Finer-Moore, Robert M Stroud, Chao Zhang, Kevan M Shokat and Peter Walter
Structural and functional basis for RNA cleavage by Ire1
BMC Biology (2011) Vol. 9(48)

2011 Alexei V Korennykh, Pascal F Egea, Andrei A Korostelev, Janet Finer-Moore, Robert M Stroud, Chao Zhang, Kevan M Shokat and Peter Walter
Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1
BMC Biology (2011) Vol. 9(48)

2011 Rubio C, Pincus D, Korennykh A, Schuck S, El-Samad H, Walter P
Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity
J Cell Biol. (2011) Vol. 193(1) pp. 171-84

2011 Plantinga MJ, Korennykh AV, Piccirilli JA, Correll CC
The ribotoxin restrictocin recognizes its RNA substrate by selective engagement of active site residues
Biochemistry (2011) Vol. 50(14) pp. 3004-13


2010 Han Li, Alexei Korennykh, Shannon Behrman, Peter Walter
ER Stress Triggers Dynamic IRE1 Clustering in Mammalian Cells
PNAS (2010) Vol. 107(37) pp. 16113-8

2009 Korennykh AV, Egea PF, Korostelev AA, Finer-Moore J, Zhang C, Shokat KM, Stroud RM, Walter P
The unfolded protein response signals through high-order assembly of Ire1
Nature (2009) Vol. 457(7230) pp. 687-93

2009 Aragón T, van Anken E, Pincus D, Serafimova IM, Korennykh AV, Rubio CA,
Walter P
Messenger RNA targeting to endoplasmic reticulum stress signaling sites
Nature (2009) Vol. 457(7230) pp. 736-40

2008 Matthew J. Plantinga, Alexei V. Korennykh, Joseph A Piccirilli, Carl C. Correll
Electrostatic interactionsguide the active site face of a structure-specific ribonuclease to its RNA substrate
Biochemistry (2008) Vol. 47(34) pp. 8912-8

2007 Alexei V. Korennykh, Matthew J. Plantinga, Carl C. Correll, Joseph A Piccirilli
Linkage Between Substrate Recognition and Catalysis During Cleavage of Sarcin/Ricin Loop RNA by Restrictocin
Biochemistry (2007) Vol. 46(44) pp. 12744-56

2007 Alexei V. Korennykh, Carl C. Correll, Joseph A Piccirilli
Evidence for the importance of electrostatics in the function of two distinct families of ribosome inactivating toxins
RNA (2007) Vol. 13(9) pp. 1391-6

2006 Alexei V. Korennykh, Joseph A Piccirilli, Carl C. Correll
The electrostatic character of the ribosomal surface enables extraordinarily rapid target location by ribotoxins
Nature Structural & Molecular Biology (2006) Vol. 13(5) pp. 436-43

2004 Shcherbakova T, Korennykh, A, Van Langen L, Sheldon R, Švedas V
Use of high acyl donor concentrations leads to penicillin acylase inactivation in the course of peptide synthesis
Journal of Molecular Catalysis B: Enzymatic (2004) Vol. 31(1-3) pp. 63-65

2003 Khimiuk A, Korennykh A, Van Langen L, Van Rantwijk F, Sheldon R, Švedas V
Penicillin acylase-catalyzed peptide synthesis in aqueous medium: a chemo-enzymatic route to stereoisomerically pure diketopiperazines
Tetrahedron: Asymmetry (2003) Vol. 14 (20) pp. 3123-3128