Donia Lab Publications

Recent Publications

MetaSUB International Consortium.
The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium inaugural meeting report.
(2016) Microbiome. 4(1): 24. | PubMed

Medema, M. H. et al.
Minimum Information about a Biosynthetic Gene cluster.
(2015) Nature Chem. Biol. 2015.11(9), 625-631. | PubMed

Donia M. S.
A toolbox for microbiome engineering.
(2015) Cell Systems 1 (1) 21-23. | PubMed

Taketani M.; Donia M. S.; Jacobson A. N.; Lambris J. D. & Fischbach M. A.
A phase-variable surface layer from the gut symbiont Bacteroides thetaiotaomicron.
(2015) mBio. 2015. 6(5): e01339-15. | PubMed

Schulze C. J.; Donia M. S.; Siqueira-Neto J. L.; Ray D.; Raskatov J. A.; Green R. E.; McKerrow J. H.; Fischbach M. A. & Linington R. G.
Genome-directed lead discovery: biosynthesis, structure elucidation, and biological evaluation of two families of polyene macrolactams against Trypanosoma brucei.
(2015) ACS Chem. Biol. 2015. 10 (10), 2373-81. | PubMed

Donia, M. S. & Fischbach, M. A.
Small molecules from the human microbiota.
(2015) Science. 349, 1254766 (2015) | PubMed

Donia MS, Cimermancic P, Schulze CJ,...Fischbach MA.
A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics.
(2014) Cell. 158: 1402-1414. | PubMed

Williams BB, Van Benschoten AH, Cimermancic P, Donia MS,...Fischbach MA. 
Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine.
(2014) Cell Host & Microbe. 16: 1-9. | PubMed
Kwan JC, Tianero MD, Donia MS, Wyche TP, Bugni, TS, Schmidt EW.
Host control of symbiont natural product chemistry in cryptic populations of the tunicate Lissoclinum patella.
(2014) PLoS One. 5: e95850 | PubMed
Marcobal A, Kashyap PC, Nelson TA,...Donia MS,...Sonnenburg JL.
A metabolomic view of how the human gut microbiota impacts the host metabolome using humanized and gnotobiotic mice.
(2013) ISME J. | PubMed

Donia MS, Fischbach MA.
Dyeing to learn more about the gut microbiota.
(2013) Cell Host Microbe. 13: 119-120. | PubMed

Kwan JC,; Donia MS, Han AW, Hirose E, Haygood MG, Schmidt EW.
Genome streamlining and chemical defense in a coral reef symbiosis.
(2012) Proc. Natl. Acad. Sci. 109: E20655-60 | PubMed

Schmidt EW, Donia MS, McIntosh JA, Fricke WF, Ravel J.
Origin and variation of tunicate secondary metabolites.
(2012) J. Nat. Prod. 75: 295-304 | PubMed

Tianero Ma D, Donia MS, Young TS, Schultz PG, Schmidt EW.
Ribosomal route to small molecule diversity.
(2012) J. Am. Chem. Soc. 134: 418-425 | PubMed

Donia MS, Fricke WF, Partensky F,...Schmidt, EW.
Complex microbiome underlying secondary and primary metabolism in the tunicate-Prochloron symbiosis.
(2011) Proc. Natl. Acad. Sci. 108: E1423-1432 | PubMed
Highlighted in Nature Biotechnology (2012) 30: 1.

McIntosh JA, Donia MS, Schmidt, EW.
Enzymatic basis of ribosomal peptide prenylation in cyanobacteria.
(2011) J. Am. Chem. Soc. 133: 34, 13698-705. |  PubMed
Highlighted in Chem. & Eng. News 89: 32, 2011

Donia MS, Ruffner DE, Cao S, Schmidt EW.
Accessing the hidden majority of marine natural products through metagenomics.
(2011) Chembiochem. 12: 1230-6. |  PubMed

Donia MS, Fricke WF, Ravel, Schmidt EW. 
Variation in tropical reef symbiont metagenomes defined by secondary metabolism.
(2011) PLoS One. 6: e17897 |  PubMed

Donia MS, Schmidt EW.
Linking chemistry and genetics in the growing cyanobactin natural products family.
(2011) Chem. & Biol. 18: 508-19. | PubMed

Publication Archive

Schmidt EW, Donia MS.
Life in cellulose houses: symbiotic bacterial biosynthesis of ascidian drugs and drug leads.
(2010) Curr. Opin. Biotechnol. 21: 827-833. | PubMed

McIntosh JA, Donia MS, Schmidt EW.
Insights into heterocyclization from two highly similar enzymes.
(2010) J. Am. Chem. Soc. 132: 4089-91. | PubMed

Donia MS, Schmidt EW. 
Cyanobactins – ubiquitous cyanobacterial ribosomal peptide metabolites.
(2010) Comprehensive Natural Products II Chemistry and Biology, Vol. 2 539-558 (Elsevier: Oxford).

Schmidt EW, Donia MS.
Cyanobactin ribosomally synthesized peptides — a case of deep genome mining.
(2009) Methods Enzymol. 458: 575-596. | PubMed

McIntosh JA, Donia MS, Schmidt EW.
Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds.
(2009) Nat. Prod. Rep. 26: 537-59. | PubMed

Donia MS, Ravel J, Schmidt EW.
A global assembly line for cyanobactins.
(2008) Nature Chem. Biol. 4: 341-3. | PubMed

Donia MS, Hathaway BJ, Sudek S, Haygood MG, Rosovitz MJ, Ravel J, Schmidt EW.
Natural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidians.
(2006) Nature Chem. Biol. 2: 729-735. | PubMed
Highlighted by Joern Piel in Nature Chem. Biol. 2006, 2, 12, 661-662.